Product Overview
- Pharmaceutical Name: Tamoxifen Citrate
- Brand Name: Nolvadex (Hubei China)
- Chemical Structure:
$$(Z)-2-[4-(1,2-diphenylbut-1-enyl)phenoxy]-N,N-dimethyl-ethanamine$$
- Product Code: HB11
- Price: $28.71
Mechanism of Action
Tamoxifen citrate is a Selective Estrogen Receptor Modulator (SERM). It operates through two primary mechanisms:
- Estrogen Inhibition: It competes with estradiol for estrogen receptors. By blocking these receptors, it prevents circulating estrogen from expressing its effects in specific tissues.
- Hormonal Recovery (Post-Cycle): In contexts where natural testosterone is suppressed, Tamoxifen prevents the activation of estrogen receptors, signaling the body to resume the production of androgens (testosterone).
Usage and Dosage
- Medical Use: Primarily indicated for the treatment of breast cancer in women.
- Alternative Use: Used as an anti-estrogen or for post-cycle therapy (PCT).
- Effective Dose: 100-150 mg/day.
- Comparison: It is functionally similar to Clomiphene (Clomid) but is considered significantly more potent per milligram.
Safety and Side Effects
While generally tolerated, users should be aware of the following potential reactions:
- Hot Flashes: Occurs in up to 80% of users.
- Common Side Effects: Nausea and headaches.
- Rare Effects: Other side effects are statistically uncommon but possible.
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